Pathway | MSEA | Meta-MSEA | Meta-GWAS | |||
---|---|---|---|---|---|---|
Finnish (n = 8330) | Framingham (n = 7572) | GLGC (n = 100184) | Without GLGC | With GLGC | ||
Lipid digestion, mobilization and transport | 4.16 | 5.46 | 6.15 | 8.67 | 13.76 | 5.00 |
Lipoprotein metabolism | 4.67 | 4.82 | 5.94 | 8.59 | 13.49 | 5.41 |
Chylomicron-mediated lipid transport | 4.88 | 4.87 | 4.72 | 8.85 | 12.61 | 5.03 |
Metabolism of lipids and lipoproteins | 3.15 | 1.71 | 6.15 | 4.00 | 8.53 | 3.56 |
Cytosolic tRNA aminoacylation | 3.58 | 2.09 | 1.92 | 4.77 | 5.86 | 2.70 |
Binding and Uptake of Ligands by Scavenger Receptors | 1.88 | 2.29 | 3.36 | 3.46 | 5.86 | 2.92 |
Scavenging by Class A Receptors | 1.83 | 2.22 | 3.22 | 3.33 | 5.62 | 3.47 |
Metabolism | 1.83 | 1.48 | 3.94 | 2.65 | 5.36 | 2.98 |
PPARA Activates Gene Expression | 1.66 | 2.22 | 2.83 | 3.17 | 5.13 | 1.33 |
Retinoid metabolism and transport | 1.01 | 2.75 | 3.04 | 2.84 | 4.94 | 1.42 |
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | 1.32 | 2.02 | 2.79 | 2.64 | 4.52 | 1.60 |
Fatty acid, triacylglycerol and ketone body metabolism | 1.48 | 1.65 | 2.49 | 2.49 | 4.13 | 1.56 |
Clathrin derived vesicle budding | 1.91 | 1.27 | 2.36 | 2.50 | 4.05 | 1.30 |
Diseases associated with visual transduction | 1.41 | 1.89 | 2.18 | 2.62 | 4.03 | 2.34 |
ABC transporters | 1.77 | 0.89 | 3.16 | 1.97 | 4.01 | 2.75 |