Fig. 4

Shifts in expression of the ‘cardiac muscle contraction’ KEGG pathway components in the cricket hindgut following cold acclimation, as an example of a pathway that was significantly differentially regulated. Each pathway component contains three color bars indicating three cold-acclimated biological replicates each compared to the mean expression among warm-acclimated replicates. For cold-acclimated crickets relative to warm-acclimated crickets, shifts in expression are either upregulated (orange), downregulated (blue), or unchanged (grey). ATP - Na⁺-K⁺ ATPase α subunit, Cyto - cytochrome c reductase iron-sulfur subunit, TPM - tropomyosin 1, Myosin - myosin heavy chain 6/7. For a complete description of each pathway component, see the KEGG ‘cardiac muscle contraction’ reference pathway (http://www.genome.jp/kegg-bin/show_pathway?ko04260)