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Table 3 Genes with alleles specific to Cluster 1 isolates

From: Hierarchical genomic analysis of carried and invasive serogroup A Neisseria meningitidis during the 2011 epidemic in Chad

Locus

Functional category

Number of mutation

Number of non-synonymous mutation

NEIS2150 (alx/TerC)

Integral membrane protein (tellurite resistance protein)

1 (bp 676)

1 (A → S)a

NMAA_0255

Insertion element IS1016 transposase

1 (bp 28)

1 (T → A)a

NEIS0947 (trpG)

Amino acid metabolism (phenylalanine, tyrosine and tryptophan biosynthesis)

1 (bp 414)

0

NMAA_0798

Hypothetical protein

1 (bp 400)

1 (E → K)a

NEIS1071

Hypothetical protein

1 (bp 461)

1 (Y → C)

NEIS1383 (aroD)

Amino acid metabolism (phenylalanine, tyrosine and tryptophan biosynthesis)

1 (bp 418)

1 (V → M)

NEIS1605

Enzyme (TatD DNase family)

1 (bp 186)

0

NEIS1742 (murG)

Glycan metabolism/Vancomycin resistance

1 (bp 632)

1 (A → V)

NEIS2135

Nicotinate and nicotinamide metabolism

1 insertion (bp 155)

15 stop codona

  1. aChange in the chemistry properties of the AA side chains