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Fig. 6 | BMC Genomics

Fig. 6

From: Transcriptional analysis of abdominal fat in chickens divergently selected on bodyweight at two ages reveals novel mechanisms controlling adiposity: validating visceral adipose tissue as a dynamic endocrine and metabolic organ

Fig. 6

Ingenuity Pathway Analysis of RNA-Seq data showed that the canonical coagulation system was over-represented by up-regulated genes in abdominal fat of LG cockerels. Plasminogen activator, urokinase (UPA) was the only coagulation gene expressed higher in visceral fat of the HG birds. The IPA indicates that 16 out of 17 DE genes are expressed at higher levels in the LG birds, while only plasmogenin activator, urokinase was up-regulated in abdominal fat of HG cockerels. Both the intrinsic (12 AR-DE genes) and extrinsic (11 AR-DE genes) pathways in visceral fat of LG birds are highly-populated by up-regulated coagulation genes (see Additional file 7 for functional AR-DE gene lists)

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BMC Genomics

ISSN: 1471-2164

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