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Fig. 5 | BMC Genomics

Fig. 5

From: Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia

Fig. 5

Heatmap showing genes differentially regulated in the nodal pathway related to DNA-damage-induced apoptosis and survival (cluster 8). The cluster combines data from 7 related pathways as shown in Additional file 2: Table S2. Selected genes depicted in the heatmap are described here. Genes related to DNA-damage-induced apoptosis and survival PW are downregulated in the WT HO group. These include Histone 2A component, H2AX contributing to the nucleosome-formation and DNA-PK i.e., DNA-dependent serine/threonine protein kinase

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BMC Genomics

ISSN: 1471-2164

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