Fig. 3
From: Germline mutation within COL2A1 associated with lethal chondrodysplasia in a polled Holstein family
Computed tomography of the skull of the bulldog calf 2 (a-c) and a control animal (d). The control animal was a Vorderwald fetus which was stillborn after 8 months of gestation. a Left lateral view displays brachygnathia superior with prolonged lower jaws (prognathism). The splanchnocranium was dysplastic in opposite to the prominent neurocranium. b In the rostrocaudal view the shortening of the nasal bones, bossing of the os frontale and the caudodorsal displacement of the orbitae are evident. c View of the oral cavity roof (mandibles had been removed). The compressed, spherical shape of the skull and the bilateral cleft palate were striking features. d The skull of the Vorderwald fetus shows an elongated and slender shape without cleft palate