Table 3 Ten most-enriched GO terms identified by the weight01 method implemented in topGO. Annotaded: number of genes annotated under the GO term; Significant: GOs identified as significant terms; Expected: number of interesting genes mapped to the GO term if the interesting genes were randomly distributed over all GO terms; Classic Fisher: test statistics based on gene counts [52]
GO.ID | Term | Annotated | Significant | Expected | classicFisher |
|---|---|---|---|---|---|
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors | 529 | 31 | 10.32 | 1.6e-07 |
GO:0050660 | flavin adenine dinucleotide binding | 494 | 29 | 9.64 | 1.8e-07 |
GO:0042302 | structural constituent of cuticle | 263 | 22 | 5.13 | 1.3e-08 |
GO:0005319 | lipid transporter activity | 164 | 15 | 3.2 | 4.7e-07 |
GO:0005200 | structural constituent of cytoskeleton | 158 | 14 | 3.08 | 2.9e-06 |
GO:0004181 | metallocarboxypeptidase activity | 153 | 11 | 2.98 | 0.00022 |
GO:0016597 | amino acid binding | 29 | 4 | 0.57 | 0.00231 |
GO:0016743 | carboxyl- or carbamoyltransferase activity | 27 | 3 | 0.53 | 0.00112 |
GO:0004743 | pyruvate kinase activity | 14 | 3 | 0.27 | 0.00229 |
GO:0003968 | RNA-directed RNA polymerase activity | 12 | 4 | 0.23 | 6.3e-05 |