Table 1 Baseline characteristics of eligible participants in the different cohorts
From: Genetic determinants of growth hormone and GH-related phenotypes
MDC-CC - Discovery | MPP - Replication | MDC - Anthropometry | |
|---|---|---|---|
Number of participants | 4134 | 5262 | 24,047 |
Female (%) | 2405 (58.2) | 1522 (28.9)*** | 14,588 (60.7)** |
Age, mean (SD), years | 57.7 (6.0) | 69.3 (6.3)*** | 58.1 (7.9)** |
Body Mass Index, mean (SD), kg/m2 | 25.8 (3.9) | 27.2 (4.2)*** | 25.8 (4.1) |
Waist, mean (SD), cm | 83.8 (12.9) | 95.8 (12.2)*** | 84.5 (13.1)** |
Waist-hip-ratio (SD) | 0.85 (0.09) | 0.93 (0.09)*** | 0.85 (0.09) |
Bodyfat percentage, mean (SD), % | 27.6 (7.1) | N/A | 26.8 (7.0)*** |
Height, mean (SD), cm | 169 (9) | 171 (9)*** | 169 (9) |
Diabetes Mellitus (%) | 367 (8.9) | 615 (11.7)*** | 1043 (4.3)*** |
Smoking (%) | 1081 (26.1) | 1028 (19.5)*** | 6338 (26.4) |
Lipid-lowering therapy (%) | 89 (2.2) | 1060 (20.1)*** | 762 (3.2)*** |
Growth Hormone - males, median (IQR), μg/L | 0.11 (0.06–0.33) | 0.40 (0.11–1.27)*** | N/A |
Growth Hormone - females, median (IQR), μg/L | 1.21 (0.38–3.12) | 0.49 (0.14–1.62)*** | N/A |