Fig. 1
From: Subfunctionalization influences the expansion of bacterial multidrug antibiotic resistance
RND 2 and 4 operon structures and hypothetical point of operon duplication. a) Schematic representation of RND 2 and 4 operon structures in B. cenocepacia J2315 genome. RND 2 operon: MFP coding gene (BCAS0766 = QU43_RS72495, 1239 bp), RND coding gene (BCAS0765 = QU43_RS72490, 3192 bp), OMP coding gene (BCAS0764 = QU43_RS72485, 1503 bp), LysR family transcriptional regulator (BCAS0767 = QU43_RS72500, 881 bp) and AraC family transcriptional regulator (BCAS0768 = QU43_RS72510, 983 bp). HP: hypothetical protein. RND 4 operon: MFP coding gene (BCAL2822 = QU43_RS50725, 1275 bp), RND coding gene (BCAL2821 = QU43_RS50720, 3201 bp), OMP coding gene (BCAL2820 = QU43_RS50715, 1524 bp), TetR family transcriptional regulator (BCAL2823 = QU43_RS50730, 641 bp). The percentages given are the degree of identity between the two operons at the nucleotide level. b) Schematic reconstruction of the phylogenetic tree reported in [19]: black triangle = RND 2 operon found in at least one strain belonging to the associated species; black circle = presence of AraC and LysR regulators coding genes associated with the operon; * = no genome belonging to this species is available