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Fig. 4 | BMC Genomics

Fig. 4

From: Identification of placental nutrient transporters associated with intrauterine growth restriction and pre-eclampsia

Fig. 4

Identification of transporters with a significantly aberrant expression pattern in gestational diseases. The expression patterns of nutrient transporters in placental tissues obtained from controls and the gestational diseases described in Fig. 3 were screened by quantitative RT–PCR. Based on Kruskal-Wallis test (p <  0.05), eight candidate transporters showed significantly altered mRNA abundance in patients, i.e. SLC7A7 (a), SLC38A2 (b), SLC38A5 (c), SLC2A1 (d), ABCA1 (e), SLC19A3 (f), SLC22A15 (g) and SLC26A2 (h). Log 2-fold change (FC) values of gene expressions are shown as scatter plots with lines drawn at median ± range. Each symbol represents the gene expression of one individual. In the same figure, the differential expression trends of transporters in IUGR or PE from the meta-analysis (see Fig. 1) are illustrated by arrows. Red and green colours depict up-regulation and down-regulation, respectively

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