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Table 3 Demographics and clinical characteristics of the studied population

From: Identification of placental nutrient transporters associated with intrauterine growth restriction and pre-eclampsia

 

Term

Preterm

IUGR

PE + IUGR

PE

p-value

Age, y

33.2

34.0

35.3

32.0

28.7

0.41, ns

[24.5-41.6]

[29.1-40.7]

[20.9-38.2]

[27.3-40.2]

[23.4-33.3]

Body mass index (BMI), kg/m2

21.3

22.8

24.6

23.3

24.1

0.32, ns

[18.6-32.8]

[21.5-28.9]

[20.8-35.5]

[19.8-26.0]

[19.8-31.9]

Gravidity

2.5

2.5

2.0

2.0

1.2

0.09, ns

[2.0-5.0]

[1.0-6.0]

[1.0-3.0]

[1.0-4.0]

[1.0-2.0]

Parity

2.0

2.0

2.0

2.0

1.0

0.06, ns

[1.0-4.0]

[1.0-3.0]

[1.0-3.0]

[1.0-3.0]

[1.0-2.0]

Gestational age, weeks

38.8

33.8**

35.9*

29.7***

33.7*

< 0.001

[38.3-39.9]

[26.1-34.6]

[21.7-39.3]

[25.3-36.3]

[25.4-36.0]

Placental weight, g

547.0

393.5

324.0*

300.0**

365.1

0.003

[398.0-1035.0]

[250.0-810.0]

[126.0-487.0]

[132.0-481.0]

[203.0-632.0]

Birth weight, g

3340.0

2127.5*

1850.0**

1170.0***

1973.5 *

< 0.001

[2950.0-3695.0]

[745.0-2510.0]

[210.0-2695.0]

[520.0-2125.0]

[605.0-2830.0]

Systolic blood pressure, mmHg

109.5

116.5

126.0

170.0***

164.4**

< 0.001

[90.0-125.0]

[100.0-146.0]

[109.0-156.0]

[150.0-200.0]

[147.0-213.0]

Diastolic blood pressure, mmHg

64.0

73.5

75.0

100.0***

98.7***

< 0.001

[50.0-83.0]

[67.0-91.0]

[63.0-94.0]

[95.0-124.0]

[93.0-104.0]

Proteinuria, g/24 h

< 0.15

< 0.15

< 0.15

0.88

2.8

 

[0.32-2.54]

[0.5-6.0]

  1. Statistical analysis was performed using Kruskal-Wallis with Dunn’s multiple comparisons test. Data are presented as median with range in brackets; ns, *, **, *** represent a p-value > 0.05, < 0.05, < 0.01, and < 0.001, respectively, of the comparison between the tested group and the term control. Details on patient selection and exclusion criteria are as described in Results (section “Identification of the altered transporter gene expression in IUGR/PE”).
  2. Abbreviations: Term, healthy pregnancies at term; Preterm, uncomplicated preterm labour; IUGR, intrauterine growth restriction; PE, pre-eclampsia; PE + IUGR, PE combined with IUGR