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Table 2 Number of deregulated miRNAs and mRNAs in aneuploid cell lines

From: The deregulated microRNAome contributes to the cellular response to aneuploidy

 

HCT116

RPE1

 

5/4

18/3 c2

*3/3 c11

*8/3 c7

5/3 12/3

*7/3

*21/3

miRNAs with a mean count ≥ 10

249

280

279

293

237

247

231

Significantly deregulated miRNAs log2 Fold Change 0.6–0.6 (padj. < 0.05)

74

57

27

44

74

33

23

Percentage of significantly deregulated miRNAs

29.7

20.4

9.7

15.0

31.2

13.4

10.0

mRNAs with a mean count ≥ 10

13,887

n.a.

n.a.

13,873

13,278

13,101

13,101

Significantly deregulated mRNAs log2 Fold Change 0.6–0.6 (padj. < 0.05)

2885

n.a.

n.a.

410

2210

434

434

Percentage of significantly deregulated mRNAs

20.8

n.a.

n.a.

3.0

16.6

n.a.

3.3

  1. Cell lines with * contain H2B-GFP