Fig. 2

A panel of 6 microRNAs was designated as circulating microRNA signature for NASH. a Top seven microRNAs were listed and ranked by their classification accuracy in two independent studies by random forest analysis. b The expression level of the microRNA signature in lean and NASH mice in study 2. Data were expressed as -ΔCt (minus delta Ct) with reference to spike-in control microRNA. c Principle component analysis (PCA) of miR-192, miR-122, miR-21, miR-29a, miR-34a, and miR-505 in study 2. Red dots represented NASH mice (mice on 3H diet for 7 months), and green dots represented lean mice. Numbers in parenthesis mean the percentage of variance explained by each principle component