Fig. 5

Development of non-invasive biomarker for NASH. a Associations between microRNAs and ALT was calculated. ALT concentration was log transformed before analysis. b, c ROC curves of the miR-192, miR-21, miR-505 and ALT in predicting mice having NAS > 3 in study 1 (AUC = 0.948, 95% confidence interval: 0.827 - 1) and study 3 (AUC = 0.931, 95% confidence interval: 0.845 - 1). The confusion matrix of study 1 was depicted in the inset