Fig. 8
From: Comparative genomic, transcriptomic, and proteomic reannotation of human herpesvirus 6
Unannotated splicing leading to C-terminal extension of HHV-6B U19 protein. Strand-specific RNA sequencing of HHV-6B cultured in Sup-T1 cells demonstrated a novel splice site at the 3′ end of the U19 transcript in the codon immediately before the annotated stop codon. The new splice site leads to a 13 amino acid C-terminal extension, which was confirmed by shotgun proteomics