Fig. 1

Lactobacillus amylovorus JBD401 reduced blood ammonia levels efficiently. a In vitro high throughput screening results showing promising probiotic strains for hyperammonemia. L. amylovorus JBD401 was especially worth noting as a candidate strain to treat hyperammonemia b, c After hyperammonemia was induced in the mouse-fed L. amylovorus JBD401, ammonia levels in its blood and brain tissue were analyzed. d, e After hyperammonemia was induced in the mouse-fed L. amylovorus JBD401, caspase 9 activity in brain tissue were analyzed. All data were expressed as the mean ± SD, as indicated. The statistical comparisons were analyzed using an unpaired Student’s t-test. All differences were considered statistically significant if p < 0.05. Statistical significance is shown as *p < 0.05, **p < 0.01 and ***p < 0.001, ^NSp > 0.05