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Fig. 2 | BMC Genomics

Fig. 2

From: Complex evolution of the GSTM gene family involves sharing of GSTM1 deletion polymorphism in humans and chimpanzees

Fig. 2

Sliding window analysis of nucleotide diversity (π) of (a) humans and (b) chimpanzees. The upper panel shows a schematic view of the compared sequences. This schema is accurate for both human and chimpanzee comparisons. Nucleotide diversity (π) between aligned 12,541b segmental duplications (window length: 500b, step size: 100b) is described. X-axis indicates chromosomal location and Y-axis indicates π values. The red dashed line indicates nucleotide diversity between segmental duplication (SD)1 and fused SD. The blue solid line indicates nucleotide diversity between human SD2 and fused SD. The putative gene conversion regions and breakpoint of the SD1 and SD2 fusion were marked in blue and yellow respectively. As indicated by blue-boxes, two gene conversion decrease the local similarity of SD1 and SDs, and the deleted allele was generated by the fusion of SD1 and SD2 at the breakpoint highlighted in yellow in both humans and chimpanzees

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