Skip to main content
Fig. 4 | BMC Genomics

Fig. 4

From: A genome-wide assessment of conserved SNP alleles reveals a panel of regulatory SNPs relevant to the peripheral nerve

Fig. 4

TRANSFAC predictions of transcription factor binding sites. TRANSFAC was used to assess for differential TFBS predictions between the major and minor alleles of SNP alleles that had a significant effect on luciferase activity. Results are shown for four regions active only in S16 cells [SC21-13 (a), SCX-67 (b), SCX-78 (c), and SCX-81 (d)], one region active only in MN1 cells [SC21-10 (e)], and three regions active in both cell types [SCX-4 (f), SCX-58 (g), and SCX-60 (h)]. Thirty base pairs surrounding the SNP alleles of each region were submitted to TRANSFAC. Dashed arrows indicate the position and direction of the predicted TFBS, the name of the transcription factor is indicated above each arrow, and the core and matrix scores are indicated at the right. Only allele-specific TFBS predictions are displayed. Underlined base pairs indicate conserved bases, and SNP alleles are highlighted in red and bold text

Back to article page