Fig. 3From: OMGene: mutual improvement of gene models through optimisation of evolutionary conservationSimplified overview of OMGene workflow. a) Gene regions are extracted from around the gene model; b) Exonerate is used to cross-align all constituent exons and full open reading frames to construct basic prototype gene models; c) The exonic regions from these prototype gene models are sorted into adjacency groups, which are then sequentially optimised using the multipartite choice function; d) Results are compared against the original gene models to incorporate potentially overlooked combinations, and filtered under various criteria to produce resultsBack to article page