Table 4 Gene Ontology (GO) terms for the 155 DE genes
GO ID | GO Function | P-value | Gene IDa |
|---|---|---|---|
GO Term BP | |||
GO:0042730 | Fibrinolysis | 7.20E-05 | FGA↓, FGB↓, FGG↓, CPB2↓ |
GO:0034116 | Positive regulation of heterotypic cell-cell adhesion | 2.20E-04 | FGA↓, FGB↓, FGG↓ |
GO: 0072378 | Blood coagulation, fibrin clot formation | 2.20E-04 | FGB↓, FGG↓, FBLN↓ |
GO: 2000352 | Negative regulation of endothelial cell apoptotic process | 3.90E-04 | NFE2L2↓, FGA↓, FGB↓, FGG↓ |
GO: 0051258 | Protein polymerization | 7.30E-04 | FGA↓, FGB↓, FGG↓ |
GO: 0031639 | Plasminogen activation | 1.10E-03 | FGA↓, FGB↓, FGG↓ |
GO: 0090277 | Positive regulation of peptide hormone secretion | 2.00E-03 | FGA↓, FGB↓, FGG↓ |
GO: 0045921 | Positive regulation of exocytosis | 3.20E-03 | FGA↓, FGB↓, FGG↓ |
GO: 0046326 | Positive regulation of glucose import | 6.30E-03 | INSR↓, NFE2L2↓, SLC1A2↑ |
GO: 1902042 | Negative regulation of extrinsic apoptotic signalling pathway via death domain receptors | 7.20E-03 | FGA↓, FGB↓, FGG↓ |
GO:0045907 | Positive regulation of vasoconstriction | 8.20E-03 | FGA↓, FGB↓, FGG↓ |
GO:0050714 | Positive regulation of protein secretion | 1.00E-02 | FGA↓, FGB↓, FGG↓ |
GO:0070527 | Platelet aggregation | 1.70E-02 | FGA↓, FGB↓, FGG↓ |
GO:0051592 | Response to calcium ion | 1.80E-02 | FGA↓, FGB↓, FGG↓ |
GO:0034599 | Cellular response to oxidative stress | 2.30E-02 | PARP1↑, SLC25A24↑, NFE2L2↓ |
GO:0043152 | Induction of bacterial agglutination | 2.60E-02 | FGA↓, FGB↓ |
GO:0010941 | Regulation of cell death | 3.40E-02 | JUN↑, SLC25A24↑ |
GO:0070374 | Positive regulation of ERK1 and ERK2 cascade | 3.60E-02 | FGA↓, FGB↓, FGG↓, JUN↑ |
GO:0007160 | Cell-matrix adhesion | 4.70E-02 | FGA↓, FGB↓, FGG↓ |
GO Term CC | |||
GO:0005577 | Fibrinogen complex | 1.30E-05 | FGA↓, FGB↓, FGG↓ |
GO:0005938 | Cell cortex | 1.20E-03 | FAM110C↑, FGA, FGG, MYO6↑ |
GO:0031091 | Platelet alpha granule | 3.30E-03 | FGA↓, FGB↓, FGG↓ |
GO:0072562 | Blood micro-particle | 7.00E-03 | AHSG↓, FGA↓, FGB↓, FGG↓ |
GO:0000785 | Chromatin | 8.90E-03 | FBXO18, MAU2, CCND2↑, NFE2L2↓ |
GO:0070062 | Extracellular exosome | 2.30E-02 | ACAA2↑, AKR1A1↑, AHSG, ANXA13↑, CDHR2↑, CPB2↓, ECI1↓, FTH1↓, FGA↓, FGG↓, FGB↓, FBLNI↓, INSR↓, MRAS↓, MYO6↑, PFKL↑, PTGDS↓, QSOX1↑, REEP5↑, TSTA3↑, UCHL1↑ |
Go Term MF | |||
GO:0005198 | Structural molecule activity | 3.50E-02 | FGA↓, FGB↓, FGG↓, NES↑ |
GO:0050662 | Coenzyme binding | 4.40E-02 | GCLC, TSTA3 |