Table 4 Results of 10-fold cross validation with datasets of virus-host PPIs using different combinations of features
From: A generalized approach to predicting protein-protein interactions between virus and host
Features | SN(%) | SP(%) | ACC(%) | PPV(%) | NPV(%) | MCC | AUC |
|---|---|---|---|---|---|---|---|
RFAT | 82.85 | 84.04 | 83.45 | 83.84 | 83.05 | 0.668 | 0.903 |
FDAT | 68.34 | 57.84 | 63.11 | 61.86 | 64.65 | 0.264 | 0.689 |
AC | 59.85 | 68.11 | 63.98 | 65.24 | 62.92 | 0.281 | 0.698 |
Composition | 71.79 | 55.79 | 63.79 | 61.89 | 66.42 | 0.279 | 0.685 |
Transition | 74.05 | 55.72 | 64.88 | 62.58 | 68.23 | 0.302 | 0.713 |
Distribution | 71.79 | 31.55 | 51.67 | 51.19 | 52.80 | 0.036 | 0.515 |
RFAT+FDAT+AC | 84.73 | 85.62 | 85.18 | 85.49 | 84.86 | 0.703 | 0.920 |
Composition+Transition +Distribution | 76.51 | 61.72 | 69.12 | 66.65 | 72.43 | 0.386 | 0.787 |
All 6 features | 85.36 | 85.92 | 85.64 | 85.84 | 85.44 | 0.712 | 0.925 |