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Table 5 Results of testing the prediction model on PPIs of new viruses

From: A generalized approach to predicting protein-protein interactions between virus and host

Dataset

SN(%)

SP(%)

ACC(%)

PPV(%)

NPV(%)

MCC

AUC

TR1–TS1

89.76

66.14

77.95

72.61

86.60

0.575

0.886

TR2–TS2

90.67

65.33

78.00

72.34

87.50

0.579

0.867

TR3–TS1

88.98

65.88

77.43

72.28

85.67

0.564

0.884

TR4–TS2

94.67

68.67

81.67

75.13

92.79

0.656

0.890

  1. TR1: training dataset of PPIs between human and any virus except H1N1. TS1: test dataset of PPIs between human and H1N1 virus. TR2: training dataset of PPIs between human and any virus except Ebola virus. TS2: test dataset of PPIs between human and Ebola virus. TR3: training dataset of PPIs between any host and any virus except H1N1. TR4: training dataset of PPIs between any host and any virus except Ebola virus. SN: sensitivity, SP: specificity, ACC: accuracy, PPV: positive predictive value, NPV: negative predictive value, MCC: Matthews correlation coefficient, AUC: area under the ROC