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Fig. 3 | BMC Genomics

Fig. 3

From: Gene expression analysis indicates reduced memory and cognitive functions in the hippocampus and increase in synaptic reorganization in the frontal cortex 3 weeks after MDMA administration in Dark Agouti rats

Fig. 3

Two-way hierarchical clustering of representative genes selected from all three brain regions. Genes modulated more than 1.5 or less than 0.5 are clustered (Euclidean distance, average linkage) into the heatmap from all three brain regions (hippocampus [HC], frontal cortex [FC] and the dorsal raphe [DR]) of Dark Agouti rats 3 weeks after a single-dose of (15 mg/kg, intraperitoneal) MDMA. The brain regions are unequivocally separated by this analysis, suggesting markedly different effects of MDMA in the different regions. See text for further details

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