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Table 3 Tuberculosis disease characteristics associated with mixed infection. Nine individuals with mixed infections based on heterozygous sites but not with the Bayesian clustering method were excluded

From: Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data

Characteristic

Mixed / Total

% mixed

P-value

Year

 1995–1999

46/539

8.5

 

 2000–2004

82/662

12.4

 

 2005–2009

44/506

8.7

 

 2010–2014

14/247

5.7

0.009

Age group (years)

  < 15

2/34

5.9

 

 15–29

61/586

10.4

 

 30–44

87/866

10.1

 

 45+

36/468

7.7

0.4

Sex

 Female

94/995

9.5

 

 Male

92/959

9.6

0.9

HIV status

 Negative

52/636

8.2

 

 Positive

69/754

9.2

 

 Positive on ART

10/120

8.3

0.8

 Unknown

55/444

12.4

 

Previous TB

 No

173/1830

9.5

 

 Yes

13/124

10.5

0.7

Lineage

 1

35/314

11.2

 

 2

14/80

17.5

 

 3

15/212

7.1

 

 4

122/1343

9.1

 

M. bovis

0/5

0.0

0.08

Type of TB

 Smear +

125/1462

8.6

 

 Smear -

53/400

13.3

 

 Extra-pulmonary

8/92

8.7

0.02

Outcome

 Completed

116/1275

9.1

 

 Died

41/405

10.1

 

 Lost/transferred

29/274

10.6

0.7

Isoniazid resistance

 Resistant

15/130

11.5

 

 Sensitive

169/1757

9.3

0.5

Rifampicin resistance

 Resistant

2/17

11.8

 

 Sensitive

182/1870

9.7

0.7

  1. P values from chi-square test except for associations with rifampicin resistance for which the Fisher exact test was used because of small numbers; ART Antiretroviral therapy