From: Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data
Characteristic | Mixed / Total | % mixed | P-value |
---|---|---|---|
Year | |||
1995–1999 | 46/539 | 8.5 | |
2000–2004 | 82/662 | 12.4 | |
2005–2009 | 44/506 | 8.7 | |
2010–2014 | 14/247 | 5.7 | 0.009 |
Age group (years) | |||
< 15 | 2/34 | 5.9 | |
15–29 | 61/586 | 10.4 | |
30–44 | 87/866 | 10.1 | |
45+ | 36/468 | 7.7 | 0.4 |
Sex | |||
Female | 94/995 | 9.5 | |
Male | 92/959 | 9.6 | 0.9 |
HIV status | |||
Negative | 52/636 | 8.2 | |
Positive | 69/754 | 9.2 | |
Positive on ART | 10/120 | 8.3 | 0.8 |
Unknown | 55/444 | 12.4 | |
Previous TB | |||
No | 173/1830 | 9.5 | |
Yes | 13/124 | 10.5 | 0.7 |
Lineage | |||
1 | 35/314 | 11.2 | |
2 | 14/80 | 17.5 | |
3 | 15/212 | 7.1 | |
4 | 122/1343 | 9.1 | |
M. bovis | 0/5 | 0.0 | 0.08 |
Type of TB | |||
Smear + | 125/1462 | 8.6 | |
Smear - | 53/400 | 13.3 | |
Extra-pulmonary | 8/92 | 8.7 | 0.02 |
Outcome | |||
Completed | 116/1275 | 9.1 | |
Died | 41/405 | 10.1 | |
Lost/transferred | 29/274 | 10.6 | 0.7 |
Isoniazid resistance | |||
Resistant | 15/130 | 11.5 | |
Sensitive | 169/1757 | 9.3 | 0.5 |
Rifampicin resistance | |||
Resistant | 2/17 | 11.8 | |
Sensitive | 182/1870 | 9.7 | 0.7 |