Fig. 1

Overview of lncRNAs in MII oocyte, CC, MEF, in vivo and two nuclear donor cell NT pre-implantation mouse embryos at different stages by single-cell RNA sequencing. a, Unsupervised hierarchical clustering across MII oocyte, CC, MEF and all types of pre-implantation embryos. b, Principal component analysis of the lncRNA expression pattern of each sample. Zygotes and 2-cell in vivo embryos were clustered together with those of the NTC and NTM groups. The numbers of samples for each stage are also indicated in the PCA. C, FPKM distributions between mRNAs with lncRNAs in MII oocyte, CC, MEF, in vivo, NTC and NTM embryos