Fig. 4
From: From mutations to mechanisms and dysfunction via computation and mining of protein energy landscapes
a-d: BDR-reconstructed landscape of H-Ras WT at two bandwidth values, 0.5 in a-b and 0.7 in c-d. The color coding-scheme is based on Amber ff14SB energy values estimated for every grid point as described in the “Methods” section. Symbols that annotate projections of select experimentally-known structures are also shown. Local minima detected by SDR at two bandwidth values are shown as black dots in b and d, respectively