Fig. 5

Up-regulation of LPS responsive genes in Fayoumi. IPA was used to identify a subset of genes known to respond to LPS with significant DE (q-value < 0.05, |log₂FC| ≥ 1.0) in Fayoumi Thermoneutral + LPS. All ten genes were up-regulated by LPS (magnitude indicated by intensity of red color). Predicted relationships between these genes, LPS, and three down-stream functions include activation (z-score ≥ 2, orange), inhibition (z-score ≤ − 2, blue), not conclusive (gray), and inconsistent (yellow). Differential expression (DE), Ingenuity Pathway Analysis (IPA), lipopolysaccharide (LPS), log₂ fold change (log₂FC)