Table 2 Top six canonical pathways most significantly (P-value< 0.001) enriched by genes differentially expressed between RE and AL groups
From: Role of AMPK signalling pathway during compensatory growth in pigs
Canonical Pathway | -log10(p-value) | Ratio | z-score | Moleculesa |
|---|---|---|---|---|
G-Protein Coupled Receptor Signaling | 4.53E00 | 2.57E-02 | – | SMPDL3A, OPRD1, PDE7B, PIK3R1, PRKAG2, DUSP4, FRS2 |
AMPK Signaling | 4.45E00 | 3.17E-02 | −1.633 | PFKFB3, PIK3R1, PRKAG2, FRS2, PFKFB2, PPARGC1A |
Relaxin Signaling | 3.85E00 | 3.29E-02 | – | SMPDL3A, PDE7B, PIK3R1, PRKAG2, FRS2 |
ERK/MAPK Signaling | 3.31E00 | 2.51E-02 | −1.342 | PLA2G4A, PIK3R1, PRKAG2, DUSP4, FRS2 |
Phagosome Formation | 3.16E00 | 3.28E-02 | – | MRC1, PIK3R1, TLR1, FRS2 |
Type II Diabetes Mellitus Signaling | 3.10E + 00 | 3.15E-02 | −1.000 | PIK3R1, CD36, PRKAG2, FRS2 |