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Fig. 3 | BMC Genomics

Fig. 3

From: Refinement of breast cancer molecular classification by miRNA expression profiles

Fig. 3

a Sample clustering and heatmap for the 15 most significant miRNAs differentially expressed between luminal A (blue) and luminal B (cyan) samples. b Corresponding gene signature activation using absolute inference of patient signatures (AIPS) model. The AIPS model uses gene expression signatures in the mRNA dataset to identify active and inactive biological processes. The AIPS algorithm assigns a random or independent value to samples, which do not show a clear active nor in-active process. Red = active, blue = inactive, white = Random/Independent

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