Fig. 4

a Survival analysis based on the mean expression of the microRNAs in the miR-99a/let-7c/miR-125b miRNA cluster. We used the median to split the patients into miR99a high (higher than median expression) and miR-99a low (lower than median expression). These groups were used in a survival analysis with R survival package, stratified based on the pam50 group and plotted using the survminer package in R. b We used the median to split the patients into LINC00478 high (higher than median expression) and LINC00478 low (lower than median expression). These groups were used in a survival analysis with R survival package, stratified based on the pam50 group and plotted using the survminer package in R We found a significant benefit for Luminal A breast cancer patients of having higher than median LINC00478 expression. c A focused analysis was done on the Luminal A samples, with ER+, HER2-, node negative, endocrine treatment, no chemotherapy and no anti-HER2 treatment. This subgroup represents 725 patients