Fig. 5

Genes with tissue-enriched expression exhibit distinct H3K27ac and H3K4me3 modifications in IGN and SOM. a and b Metagene analysis shows the average signal distribution of H3K27ac ChIP-seq and H3K4me3 ChIP-seq across gene bodies for 5075 IGN-enriched transcripts (a) and 3965 SOM-enriched transcripts (b). c-f The contribution of H3K27ac and H3K4me3 modifications (Y axis) to transcript abundance (FPKM, X axis) for genes with tissue-enriched expression in IGN and SOM (Additional files 12 and 13, Additional files 16 and 17). c IGN-H3K27ac and IGN-H3K4me3 modification status for genes with IGN-enriched expression. d SOM-H3K27ac and SOM-H3K4me3 modification status for genes with IGN-enriched expression. e IGN-H3K27ac and IGN-H3K4me3 modification status for genes with SOM-enriched expression. f SOM-H3K27ac and SOM-H3K4me3 modification status for genes with SOM-enriched expression