Fig. 7

Gene regulation network analysis of TSGs in the pig. a Degree centrality, betweenness centrality and closeness centrality between TSGs and NTSGs in pig. b Degree centrality, betweenness centrality and closeness centrality between LCTSGs, MCTSGs and HCTSGs in the pig. P values are calculated using one-sided Wilcoxon rank-sum test. * P < 0.05; ** P < 0.01; *** P < 0.001. c Density plot showing the distribution of degree centrality between 1210 porcine TSGs. The dotted line represents the value of top 5% of degree centrality. d Gene regulation network of TSGs. The edges (blue lines) indicate interactions between TSGs, while circles indicate each TSG. Blue circles indicate the hub TSGs. Only hub TSGs and their interaction genes are shown in the plot