Fig. 6

Origins are enriched at chromosomes ends. The ORI density was plotted to all 41 T. cruzi chromosomes according to their relative chromosome position, which was normalized from 0 to 100 as start and end of each chromosome. (a) Origins density and transcription orientation relative to chromosome location in S haplotype. The y-axis in a density plot is the probability density function for the kernel density estimation. (b) Overall gene density and transcription orientation along each chromosome in P haplotype. (−) Genes transcribed in the negative strand; (+) genes transcribed in the positive strand