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Table 1 Summary of evidence for horizontal gene transfer (HGT) events of SAM clusters among Fusarium species. Values in each column indicate numbers of transfer events supported by results of each analysis: NOTUNG reconciliation, constraint analysis using Shimodaira-Hasegawa and Approximately Unbiased (SH-AU) tests, and synonymous site divergence analysis

From: Identification and distribution of gene clusters required for synthesis of sphingolipid metabolism inhibitors in diverse species of the filamentous fungus Fusarium

Cluster

NOTUNG

SH-AUa

Synonymous Site Divergence (dS)b

SAM1

6

4

3 (5)

SAM2

0

0

0

SAM3

7

6

7

SAM4

11

3

3

SAM5

6

4

2

Total

30

17

15 (17)

  1. a Results of the SH-AU tests were considered to be consistent with horizontal transfer when P values from both tests were < 0.01. Given tree topologies, we were not able to assess some of the NOTUNG-inferred HGT events with the constraint/SH-AU analysis. Thus, one event for SAM3 genes, two events for SAM4 genes, and one event for SAM5 genes were not assessed by constraint/SH-AU analysis
  2. b Except those within parentheses, values indicate the number of NOTUNG-inferred transfer events that were consistent with dS values for SAM genes being less than the dS values for housekeeping genes (ratio of dS SAM genes to dS housekeeping genes, dS ratio, < 1.0). For SAM1, the value within parentheses indicates transfer events consistent with a dS ratio of 1.0–1.5 (see Methods)