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Fig. 4 | BMC Genomics

Fig. 4

From: Integrating binding and expression data to predict transcription factors combined function

Fig. 4

Differential expression of YY1 and YY2 in knockdown vs control HeLa cells. Probe intensities from microarrays of YY1 or YY2 (n = 3) knockdown and control cells (n = 3) were aggregated by gene and used to perform differential expression analysis (GSE14964). Gene expression in the YY1- and YY2-knockdown samples was compared to that of the control samples individually. a Volcano plots show the fold-change (log2) and p-values (-log 10) in each comparison. b The fold-change (log2) of the YY1- and YY2-knockdown samples are shown as a scatter plot. c The count of regulated (Up/Down) genes in by YY1 or YY2-knockdown and their intersections are shown as bars

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