Table 3 DEGs involved in different functional categories of KOG database
From: Metabolic and transcriptome responses of RNAi-mediated AMPKα knockdown in Tribolium castaneum
Categories | Up-regulated DEGs | Down-regulated DEGs | ||
|---|---|---|---|---|
NO. | Partial gene description | NO. | Partial gene description | |
Signal transduction mechanisms | 26 | tyrosine-protein phosphatase; phorbol ester/diacylglycerol-binding protein; lachesin; arf-GAP; citron Rho-interacting kinase; cyclic nucleotide-gated cation channel; E3 ubiquitin; sortilin; lipid transfer protein | 23 | neurogenic locus protein; extensin; SNF1A/AMP-activated protein kinase; cGMP-dependent phosphodiesterase; troponin C; sortilin; atrial natriuretic; sensory neuron membrane protein; regulator complex protein; tetra phosphatase |
Translation, ribosomal structure and biogenesis | 1 | eukaryotic translation initiation factor | 42 | ribosomal protein; exosome complex component; ribonuclease; H/ACA ribonucleoprotein; eukaryotic translation initiation factor |
Posttranslational modification, protein turnover, chaperones | 7 | papilin; heat shock protein 68a; pregnancy zone protein; fucosyltransferase; brain tumor protein; E3 ubiquitin; | 35 | mannosyltransferase; sulfotransferase; GILT-like protein; heat shock protein 23; ubiquitin; suppressor protein; collagenase; glutathione S-transferase; protein transport protein; NEDD8 |
Amino acid transport and metabolism | 4 | hydroxylase; protease; transporter; glucose dehydrogenase | 30 | proteinase; Carboxypeptidase; glucose dehydrogenase; trypsin |
Lipid transport and metabolism | 5 | nose resistant to fluoxetine protein; fatty acyl-CoA reductase; apolipophorins; ATP-binding cassette; Fatty acid synthetase | 17 | dehydrogenase/reductase; NADPH; alpha-tocopherol; acyl-CoA-binding protein; nose resistant to fluoxetine protein; fatty acyl-CoA reductase; desaturase; monooxygenase |
Energy production and conversion | 1 | titin isoform X4 | 23 | cytochrome b-c1 complex; stunted; ATP synthase; V-type proton ATPase; NADH dehydrogenase; cytochrome c oxidase; cytochrome b5; acylphosphatase; |
Secondary metabolites biosynthesis, transport and catabolism | 5 | fatty acyl-CoA reductase; cytochrome P450s; multidrug resistance-associated protein lethal | 12 | dehydrogenase/reductase; NADPH; laccase; fatty acyl-CoA reductase; cytochrome P450s |
Carbohydrate transport and metabolism | 1 | mucin | 6 | amylase; chitinase; lactoylglutathione lyase; glycolipid transfer protein; myrosinase; peritrophic matrix protein |