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Fig. 1 | BMC Genomics

Fig. 1

From: Analysing the meta-interaction between pathways by gene set topological impact analysis

Fig. 1

Representative pathway interactions and the design of GESTIA. a. Visualization of the gene interactions between REACTOME_MAPK1_ERK2_ ACTIVATION and REACTOME_MAPK3_ERK1_ACTIVATION. Vertices in red represent genes in the first of the two pathways, yellow represent genes in the second, and blue represent shared genes. b. Visualization of the gene interactions between REACTOME_MAPK1_ERK2_ACTIVATION and REACTOME_PI3K_ AKT_ACTIVATION. The color set of the vertices is the same as in a. c. Visualization of the gene interactions between BIOCARTA_MTOR_PATHWAY and REACTOME_PI3K_ AKT_ACTIVATION. from MSigDB. The color set of the vertices is the same as in a. d. The design of GESTIA. The color set of the vertices is the same as in a, and green represent pseudo-vertices

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