Fig. 5
From: Long non-coding RNA exploration for mesenchymal stem cell characterisation
Prediction of potential functions of the candidates with k-mer quantification and single-cell. For each Mlinc (Mlinc.28428 (a) Mlinc.128022 (b) and Mlinc.89912 (c) respectively) 3 steps of prediction were performed. a Enrichment in the different subcompartments of fibroblasts from FANTOM6 dataset: free nuclear fraction (Nuc), chromatin (Chr) and cytoplasm (Cyt); b Expression of markers in FANTOM6 data depending of the Knock-down (KD) of annotated lncRNAs. Normalised counts of all specific k-mers is averaged by sample (zero values deleted) and t-tests are made between control (in pink) and KD fibroblasts (in turquoise). c General expression of Mlincs inside Ad-MSC population, dimensional reduction made with UMAP method, made from batch corrected counts. Expression of differentially expressed annotated genes between positive (in turquoise) and negative (in pink) cells for Mlinc.28428, Mlinc.128022 and Mlinc.89912 respectively