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Fig. 1 | BMC Genomics

Fig. 1

From: Millefy: visualizing cell-to-cell heterogeneity in read coverage of single-cell RNA sequencing datasets

Fig. 1

Overview of Millefy. a Millefy imports scRNA-seq data and visualizes read coverage of individual cells as a heat map. The rows (i.e., cells) of the heat map are dynamically reordered by diffusion maps. This automatic reordering highlights cell-to-cell heterogeneity in read coverage, which is hidden by mean read coverage data. Millefy associates genomic contexts, including bulk NGS data, genomic features, and gene annotations, thus facilitating the interpretation of single-cell read coverage. The parallelograms represent different types of input data. Gray boxes represent displayed tracks in Millefy. White boxes represent computation of a read coverage matrix. b An example plot in Millefy

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