Fig. 7

Multiple sequence alignment of the putative RiPP precursor peptide from cluster 55. The putative RiPP precursor peptide from T. reesei was aligned to the 20 top hits from the Blastp output using the ClustalW algorithm and was performed with PRALINE [28]. The 21 aligned amino acid sequences are colored according to the ClustalX residue color-scheme. The row labeled ‘Consistency’ is color-coded based on the amino acid conservation performed by PRALINE, 0 representing the least conserved alignment position colored in blue up to 10 marked by an asterix in red. Below the Consistency row the blue and red colored blocks stand for the representative secondary structure prediction using DSSP and PSIPRED. The β-Strand predictions are colored in blue and the red colored blocks are the α-Helix predictions. The predicted putative core peptide sequence is indicated by a black frame