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Fig. 4 | BMC Genomics

Fig. 4

From: The effect of antibiotics on the gut microbiome: a metagenomics analysis of microbial shift and gut antibiotic resistance in antibiotic treated mice

Fig. 4

a-c Change in the number of statistically significant genera detected in treatment samples compared to control samples based on 16S rRNA analysis. The 16S rRNA sequences were re-constructed from metagenome shotgun and taxonomy was assigned using Metaxa2 and SILVA database. metagenomeSeq used to find bacterial genera that were statistically significant, differentially represented between control and treatment time points (24, 48, and 72 h) after oral treatment with Ampicilin (a), Ciprofloxacin (b), or Fosfomycin (c). Green bars represent number of genera at each time point (24, 48, and 72 h) that exhibited a decreased relative abundance compared to control. Red bars represent number of genera that exhibited increased relative abundance. A list of these genera for each cohort/treatment combination along with their fold change values is provided in Supplementary Information Table 2a-i

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