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Fig. 7 | BMC Genomics

Fig. 7

From: The metabolome as a link in the genotype-phenotype map for peroxide resistance in the fruit fly, Drosophila melanogaster

Fig. 7

Knockdown of Genes in Glycogen or Folate Metabolism. F1 females from crosses of UAS-RNAi lines, targeting the indicated gene with either the GeneSwitch106 (106GS, top row), GeneSwitch32 (32GS, middle row), or elavGeneSwitch (elavGS, bottom row) drivers, were maintained on RU486 food (dashed line) or –RU control food (solid line) for 48 h prior to being transferred to H2O2 or control food. Survivorship was recorded for five replicate vials of ten flies per vial on H2O2 food and two to five replicates on control food (n = 20 or 5 flies). Asterisks indicate significant effect of RU486 (P < 0.05, log-rank test). Data are representative of one or two experiments, and the mortality of flies on control food (not shown) did not exceed 15% in any condition and did not depend on RU486 exposure

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