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Fig. 13 | BMC Genomics

Fig. 13

From: Inferring time series chromatin states for promoter-enhancer pairs based on Hi-C data

Fig. 13

DAGs of Bayesian network for clustering feature regions (top) and promoter-enhancer feature pairs (bottom). Colors represent different histone modifications (green: H3K27ac, red: H3K27me3, black: H3K4me1, orange: H3K4me2, gray: H3K4me3). For clustering of feature regions from mouse hematopoiesis data (top) there are 4 histone modifications and 5 time intervals, therefore the DAG consists of 21 nodes. For clustering of promoter-enhancer feature pairs from human pancreatic differentiation (bottom) there are 4 histone modifications and 3 time intervals resulting in 25 nodes. One half of the continuous nodes represents histone mark signals of the promoter side and the other half represents histone mark signals of the enhancer side

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