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Table 5 Comparing p-values for EcoCyc VALSYN-PWY and KEGG map00290

From: Pathway size matters: the influence of pathway granularity on over-representation (enrichment analysis) statistics

Count of Significantly Expressed Genes

EcoCyc p-value

Corrected for Multiple Comparisons

Native KEGG p-value

Corrected for Multiple Comparisons

9

1.6×10−22

5.8×10−20

3.9×10−20

4.6×10−18

8

1.8×10−19

6.3×10−17

8.1×10−18

9.6×10−16

7

9.7×10−17

3.4×10−14

1.5×10−15

1.8×10−13

6

3.5×10−14

1.3×10−11

2.5×10−13

3.0×10−11

5

9.6×10−12

3.4×10−9

3.9×10−11

4.6×10−9

4

2.1×10−9

7.5×10−7

5.4×10−9

6.5×10−7

3

3.8×10−7

1.4×10−4

7.0×10−7

8.4×10−5

2

6.0×10−5

2.1×10−2

8.4×10−5

1.0×10−2

1

8.2×10−3

1.0

9.4×10−3

1.0

  1. Corrected p-values use Bonferroni as a ’worst case’ correction as discussed in the text