A fast wavelet-based functional association analysis replicates several susceptibility loci for birth weight in a Norwegian population

Table 1 Summary of the regions detected by the modified WaveQTL

Chr	Start (bp)	End (bp)	Main	P-value	Corresponding	Gene name	GWAMA	Sample
			run		correction			size
1	43340639	43403139	Yes	5.06×10⁻⁷	9.67×10⁻⁶	SLC2A1	[1]	230,069
3	123051305	123133336	Yes	9.81×10⁻⁸	9.67×10⁻⁶	ADCY5	[21]	27,591
3	156785678	156816928	No	7.00×10⁻⁸	3.04×10⁻⁷	LOC339894/CCNL1	[16]	61,142
8	142201004	142255692	No	1.01×10⁻⁷	6.08×10⁻⁷	SLC45A4	[16]	61,142
17	6965237	7215238	Yes	2.82×10⁻⁸	9.67×10⁻⁶	CLDN7/SLC2A4	[15]	153,781

In the column “Main run”, “Yes” corresponds to a region detected using the modified WaveQTL, and “No” corresponds to a region subsequently detected only after applying the zooming strategy. The column “Corresponding correction” displays the nominal significance level for declaring a region as statistically significant (see Methods for details). The column “GWAMA” corresponds to the GWAMA in which the locus was first detected. The column “Sample Size” corresponds to the sample size of the GWAMA in which the locus was first detected. The genomic coordinates are based on the GRCh37 hg19 genome assembly

ISSN: 1471-2164