Skip to main content

Table 1 Statistics of selected epitopes

From: Employing computational tools to design a multi-epitope vaccine targeting human immunodeficiency virus-1 (HIV-1)

Sr. No

Epitopes

Symbol

Protein

Position

HLA-1/HLA-2

Antigenicity

BLASTp (E-score)

Toxicity (SVM value)

Conservancy

1

APRKKGCWK

NC1

Nucleocapsid

30–38

HLA-1

0.6832

28

-0.48

83.88

2

PRKKGCWKC

NC2

Nucleocapsid

31–39

HLA-1

1.4065

55

-0.26

83.94

3

RKKGCWKCG

NC3

Nucleocapsid

32–40

HLA-1

1.5171

55

-0.1

83.94

4

PLTEEKIKA

RT1

Reverse Transcriptase

25–33

HLA-1

0.7833

13

-1.4

92.85

5

KRTQDFWEV

RT2

Reverse Transcriptase

82–90

HLA-1

1.1553

1.6

-1.49

91.78

6

RTQDFWEVQ

RT3

Reverse Transcriptase

83–91

HLA-1

1.421

1.6

-1.61

91.86

7

TQDFWEVQL

RT4

Reverse Transcriptase

84–92

HLA-1

0.716

1.6

-1.79

95.45

8

AHKGIGGNE

RT5

Reverse Transcriptase

538–546

HLA-1

0.6955

78

-1.05

98.21

9

FRVYYRDSR

Int1

Integrase

223–231

Both

0.8423

6.7

-1.36

88.12

10

VYYRDSRDP

Int2

Integrase

225–233

HLA-2

0.7874

1.2

-0.86

86.67

11

ERAEDSGNE

VPU1

VPU

48–56

HLA-1

0.6154

4.7

-1.14

82.84

  1. Symbols adapted, parent proteins, reference protein positions, Targeted HLA type, antigenicity, BLASTp analysis with human proteome, toxicity, and conservancy analysis of selected epitopes