Skip to main content

Articles

Page 268 of 332

  1. Microarray gene expression data are accumulating in public databases. The expression profiles contain valuable information for understanding human gene expression patterns. However, the effective use of public...

    Authors: Liangjiang Wang, Anand K Srivastava and Charles E Schwartz
    Citation: BMC Genomics 2010 11(Suppl 2):S15
    Content type: Research Published on:

    This article is part of a Supplement: Volume 11 Supplement 2

  2. Long branch attraction (LBA) is a problem that afflicts both the parsimony and maximum likelihood phylogenetic analysis techniques. Research has shown that parsimony is particularly vulnerable to inferring the...

    Authors: Timothy O’Connor, Kenneth Sundberg, Hyrum Carroll, Mark Clement and Quinn Snell
    Citation: BMC Genomics 2010 11(Suppl 2):S14
    Content type: Research Published on:

    This article is part of a Supplement: Volume 11 Supplement 2

  3. Breast cancer is worldwide the second most common type of cancer after lung cancer. Plasma proteome profiling may have a higher chance to identify protein changes between plasma samples such as normal and brea...

    Authors: Fan Zhang and Jake Y Chen
    Citation: BMC Genomics 2010 11(Suppl 2):S12
    Content type: Research Published on:

    This article is part of a Supplement: Volume 11 Supplement 2

  4. A large amount of functional genomic data have provided enough knowledge in predicting gene function computationally, which uses known functional annotations and relationship between unknown genes and known on...

    Authors: Yiming Chen, Zhoujun Li, Xiaofeng Wang, Jiali Feng and Xiaohua Hu
    Citation: BMC Genomics 2010 11(Suppl 2):S11
    Content type: Research Published on:

    This article is part of a Supplement: Volume 11 Supplement 2

  5. Identification of protein complexes in large interaction networks is crucial to understand principles of cellular organization and predict protein functions, which is one of the most important issues in the po...

    Authors: Jianxin Wang, Binbin Liu, Min Li and Yi Pan
    Citation: BMC Genomics 2010 11(Suppl 2):S10
    Content type: Research Published on:

    This article is part of a Supplement: Volume 11 Supplement 2

  6. Ultrasound imaging technology has wide applications in cattle reproduction and has been used to monitor individual follicles and determine the patterns of follicular development. However, the speckles in ultra...

    Authors: Jinshan Tang, Shengwen Guo, Qingling Sun, Youping Deng and Dongfeng Zhou
    Citation: BMC Genomics 2010 11(Suppl 2):S9
    Content type: Research Published on:

    This article is part of a Supplement: Volume 11 Supplement 2

  7. Modern approaches to treating genetic disorders, cancers and even epidemics rely on a detailed understanding of the underlying gene signaling network. Previous work has used time series microarray data to infe...

    Authors: David Oviatt, Mark Clement, Quinn Snell, Kenneth Sundberg, Chun Wan J Lai, Jared Allen and Randall Roper
    Citation: BMC Genomics 2010 11(Suppl 2):S6
    Content type: Research Published on:

    This article is part of a Supplement: Volume 11 Supplement 2

  8. Protein destabilization is a common mechanism by which amino acid substitutions cause human diseases. Although several machine learning methods have been reported for predicting protein stability changes upon ...

    Authors: Shaolei Teng, Anand K Srivastava and Liangjiang Wang
    Citation: BMC Genomics 2010 11(Suppl 2):S5
    Content type: Research Published on:

    This article is part of a Supplement: Volume 11 Supplement 2

  10. Identification of differentially expressed genes from microarray datasets is one of the most important analyses for microarray data mining. Popular algorithms such as statistical t-test rank genes based on a s...

    Authors: Jianjun Hu and Jia Xu
    Citation: BMC Genomics 2010 11(Suppl 2):S3
    Content type: Proceedings Published on:

    This article is part of a Supplement: Volume 11 Supplement 2

  11. Many essential cellular processes, such as cellular metabolism, transport, cellular metabolism and most regulatory mechanisms, rely on physical interactions between proteins. Genome-wide protein interactome ne...

    Authors: Feng Xu, Guang Li, Chen Zhao, Yuhua Li, Peng Li, Jian Cui, Youping Deng and Tieliu Shi
    Citation: BMC Genomics 2010 11(Suppl 2):S2
    Content type: Research Published on:

    This article is part of a Supplement: Volume 11 Supplement 2

  12. Genomic islands (GIs) are clusters of alien genes in some bacterial genomes, but not be seen in the genomes of other strains within the same genus. The detection of GIs is extremely important to the medical an...

    Authors: Dongsheng Che, Cory Hockenbury, Robert Marmelstein and Khaled Rasheed
    Citation: BMC Genomics 2010 11(Suppl 2):S1
    Content type: Research Published on:

    This article is part of a Supplement: Volume 11 Supplement 2

  13. The shell of the pearl-producing bivalve Pinctada margaritifera is composed of an organic cell-free matrix that plays a key role in the dynamic process of biologically-controlled biomineralization. In order to in...

    Authors: Caroline Joubert, David Piquemal, Benjamin Marie, Laurent Manchon, Fabien Pierrat, Isabelle Zanella-Cléon, Nathalie Cochennec-Laureau, Yannick Gueguen and Caroline Montagnani
    Citation: BMC Genomics 2010 11:613
    Content type: Research article Published on:

  14. Several Echinacea species have been used as nutraceuticals or botanical drugs for "immunostimulation", but scientific evidence supporting their therapeutic use is still controversial. In this study, a phytocompou...

    Authors: Shu-Yi Yin, Wen-Hsin Wang, Pei-Hsueh Wang, Kandan Aravindaram, Pei-Ing Hwang, Han-Ming Wu and Ning-Sun Yang
    Citation: BMC Genomics 2010 11:612
    Content type: Research article Published on:

  15. Apoptosis is regulated in an orderly fashion by a series of genes, and has a crucial role in important physiological processes such as growth development, immunological response and so on. Recently, substantia...

    Authors: Jin-Ye Zhang, Min-Hui Pan, Zhi-Ya Sun, Shu-Jing Huang, Zi-Shu Yu, Di Liu, Dan-Hong Zhao and Cheng Lu
    Citation: BMC Genomics 2010 11:611
    Content type: Research article Published on:

  16. Trypanosoma cruzi is the etiological agent of Chagas' disease, an endemic infection that causes thousands of deaths every year in Latin America. Therapeutic options remain inefficient, demanding the search for ne...

    Authors: Priscila VSZ Capriles, Ana CR Guimarães, Thomas D Otto, Antonio B Miranda, Laurent E Dardenne and Wim M Degrave
    Citation: BMC Genomics 2010 11:610
    Content type: Research article Published on:

  17. Dysregulated expression of microRNAs (miRNAs) has been previously observed in human cancer tissues and shown promise in defining tumor status. However, there is little information as to if or when expression c...

    Authors: Zhiguang Li, William S Branham, Stacey L Dial, Yexun Wang, Lei Guo, Leming Shi and Tao Chen
    Citation: BMC Genomics 2010 11:609
    Content type: Research article Published on:

  18. Adenosine to inosine (A-to-I) RNA-editing is an essential post-transcriptional mechanism that occurs in numerous sites in the human transcriptome, mainly within Alu repeats. It has been shown to have consisten...

    Authors: Shoshana Greenberger, Erez Y Levanon, Nurit Paz-Yaacov, Aviv Barzilai, Michal Safran, Sivan Osenberg, Ninette Amariglio, Gideon Rechavi and Eli Eisenberg
    Citation: BMC Genomics 2010 11:608
    Content type: Research article Published on:

  20. Jatropha curcas L. is promoted as an important non-edible biodiesel crop worldwide. Jatropha oil, which is a triacylglycerol, can be directly blended with petro-diesel or transesterified with methanol and used as...

    Authors: Purushothaman Natarajan, Deepa Kanagasabapathy, Gnanasekaran Gunadayalan, Jasintha Panchalingam, Noopur shree, Priyanka Annabel Sugantham, Kavita Kumari Singh and Parani Madasamy
    Citation: BMC Genomics 2010 11:606
    Content type: Research article Published on:

  21. The genus Bothrops is widespread throughout Central and South America and is the principal cause of snakebite in these regions. Transcriptomic and proteomic studies have examined the venom composition of several ...

    Authors: Kiara C Cardoso, Márcio J Da Silva, Gustavo GL Costa, Tatiana T Torres, Luiz Eduardo V Del Bem, Ramon O Vidal, Marcelo Menossi and Stephen Hyslop
    Citation: BMC Genomics 2010 11:605
    Content type: Research article Published on:

  22. Sweetpotato (Ipomoea batatas (L.) Lam.), a hexaploid outcrossing crop, is an important staple and food security crop in developing countries in Africa and Asia. The availability of genomic resources for sweetpota...

    Authors: Roland Schafleitner, Luz R Tincopa, Omar Palomino, Genoveva Rossel, Ronald F Robles, Rocio Alagon, Carlos Rivera, Cynthia Quispe, Luis Rojas, Jaime A Pacheco, Julio Solis, Diogenes Cerna, Ji Young Kim, Jack Hou and Reinhard Simon
    Citation: BMC Genomics 2010 11:604
    Content type: Research article Published on:

  23. Microarrays are invaluable tools for genome interrogation, SNP detection, and expression analysis, among other applications. Such broad capabilities would be of value to many pathogen research communities, alt...

    Authors: Amit Bahl, Paul H Davis, Michael Behnke, Florence Dzierszinski, Manjunatha Jagalur, Feng Chen, Dhanasekaran Shanmugam, Michael W White, David Kulp and David S Roos
    Citation: BMC Genomics 2010 11:603
    Content type: Research article Published on:

  24. The ectoparasitic mite Varroa destructor has emerged as the primary pest of domestic honey bees (Apis mellifera). Here we present an initial survey of the V. destructor genome carried out to advance our understan...

    Authors: R Scott Cornman, Michael C Schatz, J Spencer Johnston, Yan-Ping Chen, Jeff Pettis, Greg Hunt, Lanie Bourgeois, Chris Elsik, Denis Anderson, Christina M Grozinger and Jay D Evans
    Citation: BMC Genomics 2010 11:602
    Content type: Research article Published on:

  26. Glycoside hydrolases cleave the bond between a carbohydrate and another carbohydrate, a protein, lipid or other moiety. Genes encoding glycoside hydrolases are found in a wide range of organisms, from archea t...

    Authors: Ludmila Tyler, Jennifer N Bragg, Jiajie Wu, Xiaohan Yang, Gerald A Tuskan and John P Vogel
    Citation: BMC Genomics 2010 11:600
    Content type: Research article Published on:

  28. Microsatellites are the most popular source of molecular markers for studying population genetic variation in eukaryotes. However, few data are currently available about their genomic distribution and abundanc...

    Authors: Philippe Castagnone-Sereno, Etienne GJ Danchin, Emeline Deleury, Thomas Guillemaud, Thibaut Malausa and Pierre Abad
    Citation: BMC Genomics 2010 11:598
    Content type: Research article Published on:

  29. The family Tetranychidae (Chelicerata: Acari) includes ~1200 species, many of which are of agronomic importance. To date, mitochondrial genomes of only two Tetranychidae species have been sequenced, and it has...

    Authors: Ming-Long Yuan, Dan-Dan Wei, Bao-Jun Wang, Wei Dou and Jin-Jun Wang
    Citation: BMC Genomics 2010 11:597
    Content type: Research article Published on:

  30. Anabolic steroids, such as nandrolone, slow muscle atrophy, but the mechanisms responsible for this effect are largely unknown. Their effects on muscle size and gene expression depend upon time, and the cause ...

    Authors: Weiping Qin, Jiangping Pan, William A Bauman and Christopher P Cardozo
    Citation: BMC Genomics 2010 11:596
    Content type: Research article Published on:

  31. Many plant species have been investigated in the last years for the identification and characterization of the corresponding miRNAs, nevertheless extensive studies are not yet available on barley (at the time ...

    Authors: Moreno Colaiacovo, Annalisa Subacchi, Paolo Bagnaresi, Antonella Lamontanara, Luigi Cattivelli and Primetta Faccioli
    Citation: BMC Genomics 2010 11:595
    Content type: Research article Published on:

  32. The Multinational Brassica rapa Genome Sequencing Project (BrGSP) has developed valuable genomic resources, including BAC libraries, BAC-end sequences, genetic and physical maps, and seed BAC sequences for Brassi...

    Authors: Jinsong Xu, Xiaoju Qian, Xiaofeng Wang, Ruiyuan Li, Xiaomao Cheng, Yuan Yang, Jie Fu, Shunchang Zhang, Graham J King, Jiangsheng Wu and Kede Liu
    Citation: BMC Genomics 2010 11:594
    Content type: Research article Published on:

  33. Recent studies in pigs have detected copy number variants (CNVs) using the Comparative Genomic Hybridization technique in arrays designed to cover specific porcine chromosomes. The goal of this study was to id...

    Authors: Yuliaxis Ramayo-Caldas, Anna Castelló, Romi N Pena, Estefania Alves, Anna Mercadé, Carla A Souza, Ana I Fernández, Miguel Perez-Enciso and Josep M Folch
    Citation: BMC Genomics 2010 11:593
    Content type: Research article Published on:

  34. Flax (Linum usitatissimum L.) has been cultivated for around 9,000 years and is therefore one of the oldest cultivated species. Today, flax is still grown for its oil (oil-flax or linseed cultivars) and its cellu...

    Authors: Stéphane Fenart, Yves-Placide Assoumou Ndong, Jorge Duarte, Nathalie Rivière, Jeroen Wilmer, Olivier van Wuytswinkel, Anca Lucau, Emmanuelle Cariou, Godfrey Neutelings, Laurent Gutierrez, Brigitte Chabbert, Xavier Guillot, Reynald Tavernier, Simon Hawkins and Brigitte Thomasset
    Citation: BMC Genomics 2010 11:592
    Content type: Research article Published on:

  35. The Enterobacteriaceae comprise a large number of clinically relevant species with several individual subspecies. Overlapping virulence-associated gene pools and the high overall genome plasticity often interfere...

    Authors: Torben Friedrich, Sven Rahmann, Wilfried Weigel, Wolfgang Rabsch, Angelika Fruth, Eliora Ron, Florian Gunzer, Thomas Dandekar, Jörg Hacker, Tobias Müller and Ulrich Dobrindt
    Citation: BMC Genomics 2010 11:591
    Content type: Research article Published on:

  36. Peroxide turnover and signalling are involved in many biological phenomena relevant to human diseases. Yet, all the players and mechanisms involved in peroxide perception are not known. Elucidating very remote...

    Authors: Krzysztof Pawłowski, Anna Muszewska, Anna Lenart, Teresa Szczepińska, Adam Godzik and Marcin Grynberg
    Citation: BMC Genomics 2010 11:590
    Content type: Research article Published on:

  37. Since human brain tissue is often unavailable for transcriptional profiling studies, blood expression data is frequently used as a substitute. The underlying hypothesis in such studies is that genes expressed ...

    Authors: Chaochao Cai, Peter Langfelder, Tova F Fuller, Michael C Oldham, Rui Luo, Leonard H van den Berg, Roel A Ophoff and Steve Horvath
    Citation: BMC Genomics 2010 11:589
    Content type: Research article Published on:

  38. Gene duplication is a normal evolutionary process. If there is no selective advantage in keeping the duplicated gene, it is usually reduced to a pseudogene and disappears from the genome. However, some paralog...

    Authors: Marit S Bratlie, Jostein Johansen, Brad T Sherman, Da Wei Huang, Richard A Lempicki and Finn Drabløs
    Citation: BMC Genomics 2010 11:588
    Content type: Research article Published on:

  39. The bacterium Pseudomonas aeruginosa is capable of three types of motilities: swimming, twitching and swarming. The latter is characterized by a fast and coordinated group movement over a semi-solid surface resul...

    Authors: Julien Tremblay and Eric Déziel
    Citation: BMC Genomics 2010 11:587
    Content type: Research article Published on:

  40. A resequencing microarray called PathogenID v2.0 has been developed and used to explore various strategies of sequence selection for its design. The part dedicated to influenza viruses was based on consensus s...

    Authors: India Leclercq, Nicolas Berthet, Christophe Batéjat, Claudine Rousseaux, Philip Dickinson, Iain G Old, Katherine Kong, Giulia C Kennedy, Stewart T Cole and Jean-Claude Manuguerra
    Citation: BMC Genomics 2010 11:586
    Content type: Methodology article Published on:

  41. The current study focused on the extent genetic diversity within a species (Mus musculus) affects gene co-expression network structure. To examine this issue, we have created a new mouse resource, a heterogeneous...

    Authors: Ovidiu D Iancu, Priscila Darakjian, Nicole AR Walter, Barry Malmanger, Denesa Oberbeck, John Belknap, Shannon McWeeney and Robert Hitzemann
    Citation: BMC Genomics 2010 11:585
    Content type: Research article Published on:

  42. The ecological niche occupied by a fungal species, its pathogenicity and its usefulness as a microbial cell factory to a large degree depends on its secretome. Protein secretion usually requires the presence o...

    Authors: Machtelt Braaksma, Elena S Martens-Uzunova, Peter J Punt and Peter J Schaap
    Citation: BMC Genomics 2010 11:584
    Content type: Research article Published on:

  43. Two year cancer bioassays conducted by the National Toxicology Program have shown chronic exposure to dioxin-like compounds (DLCs) to lead to the development of both neoplastic and non-neoplastic lesions in th...

    Authors: Bladimir J Ovando, Corie A Ellison, Chad M Vezina and James R Olson
    Citation: BMC Genomics 2010 11:583
    Content type: Research article Published on:

  44. All crustaceans periodically moult to renew their exoskeleton. In krill this involves partial digestion and resorption of the old exoskeleton and synthesis of new cuticle. Molecular events that underlie the mo...

    Authors: Paul J Seear, Geraint A Tarling, Gavin Burns, William P Goodall-Copestake, Edward Gaten, Özge Özkaya and Ezio Rosato
    Citation: BMC Genomics 2010 11:582
    Content type: Research article Published on:

  45. How the transcription factor binding sites (TFBSs) are distributed in the promoter region have implications for gene regulation. Previous studies used the translation start codon as the reference point to infe...

    Authors: Zhenguo Lin, Wei-Sheng Wu, Han Liang, Yong Woo and Wen-Hsiung Li
    Citation: BMC Genomics 2010 11:581
    Content type: Research article Published on:

  47. Understanding ethanol tolerance in microorganisms is important for the improvement of bioethanol production. Hence, we performed parallel-evolution experiments using Escherichia coli cells under ethanol stress to...

    Authors: Takaaki Horinouchi, Kuniyasu Tamaoka, Chikara Furusawa, Naoaki Ono, Shingo Suzuki, Takashi Hirasawa, Tetsuya Yomo and Hiroshi Shimizu
    Citation: BMC Genomics 2010 11:579
    Content type: Research article Published on:

  48. Elevated parasite biomass in the human red blood cells can lead to increased malaria morbidity. The genes and mechanisms regulating growth and development of Plasmodium falciparum through its erythrocytic cycle a...

    Authors: Heather B Reilly Ayala, Mark A Wacker, Geoffrey Siwo and Michael T Ferdig
    Citation: BMC Genomics 2010 11:577
    Content type: Research article Published on:

  49. The immune system of the purple sea urchin, Strongylocentrotus purpuratus, is complex and sophisticated. An important component of sea urchin immunity is the Sp185/333 gene family, which is significantly upregula...

    Authors: Chase A Miller, Katherine M Buckley, Rebecca L Easley and L Courtney Smith
    Citation: BMC Genomics 2010 11:575
    Content type: Research article Published on:

  50. The human pathogen Listeria monocytogenes resides and proliferates within the cytoplasm of epithelial cells. While the virulence factors essentially contributing to this step of the infection cycle are well chara...

    Authors: Kristina Schauer, Gernot Geginat, Chunguang Liang, Werner Goebel, Thomas Dandekar and Thilo M Fuchs
    Citation: BMC Genomics 2010 11:573
    Content type: Research article Published on:

Featured videos

View featured videos from across the BMC-series journals

Submit manuscript

Annual Journal Metrics

  • 2022 Citation Impact
    4.4 - 2-year Impact Factor
    4.7 - 5-year Impact Factor
    1.189 - SNIP (Source Normalized Impact per Paper)
    1.107 - SJR (SCImago Journal Rank)

    2023 Speed
    23 days submission to first editorial decision for all manuscripts (Median)
    137 days submission to accept (Median)

    2023 Usage
    7,167,242 downloads
    4,454 Altmetric mentions

Follow

Sign up for article alerts and news from this journal

BMC Genomics

ISSN: 1471-2164

Contact us