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  1. The newly discovered reversible N6-methyladenosine (m6A) modification plays an important regulatory role in gene expression. Long non-coding RNAs (lncRNAs) participate in Marek’s disease virus (MDV) replication b...

    Authors: Aijun Sun, Xiaojing Zhu, Ying Liu, Rui Wang, Shuaikang Yang, Man Teng, Luping Zheng, Jun Luo, Gaiping Zhang and Guoqing Zhuang

    Citation: BMC Genomics 2021 22:296

    Content type: Research

    Published on:

  2. Sorghum grain mold is the most important disease of the crop. The disease results from simultaneous infection of the grain by multiple fungal species. Host responses to these fungi and the underlying molecular...

    Authors: Habte Nida, Sanghun Lee, Ying Li and Tesfaye Mengiste

    Citation: BMC Genomics 2021 22:295

    Content type: Research

    Published on:

  3. The feed conversion ratio (FCR) is an important productive trait that greatly affects profits in the pig industry. Elucidating the genetic mechanisms underpinning FCR may promote more efficient improvement of ...

    Authors: Yuanxin Miao, Quanshun Mei, Chuanke Fu, Mingxing Liao, Yan Liu, Xuewen Xu, Xinyun Li, Shuhong Zhao and Tao Xiang

    Citation: BMC Genomics 2021 22:294

    Content type: Research article

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  4. Most Distylium species are endangered. Distylium species mostly display homoplasy in their flowers and fruits, and are classified primarily based on leaf morphology. However, leaf size, shape, and serration vary ...

    Authors: Wenpan Dong, Yanlei Liu, Chao Xu, Yongwei Gao, Qingjun Yuan, Zhili Suo, Zhixiang Zhang and Jiahui Sun

    Citation: BMC Genomics 2021 22:293

    Content type: Research article

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  5. Yersinia ruckeri is a pathogen that can cause enteric redmouth disease in salmonid species, damaging global production of economically important fish including rainbow trout (Oncorhynchus mykiss). Herein, we cond...

    Authors: Di Wang, Simeng Sun, Shaowu Li, Tongyan Lu and Dongfang Shi

    Citation: BMC Genomics 2021 22:292

    Content type: Research

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  7. The key-ancestor approach has been frequently applied to prioritize individuals for whole-genome sequencing based on their marginal genetic contribution to current populations. Using this approach, we selected...

    Authors: Adéla Nosková, Meenu Bhati, Naveen Kumar Kadri, Danang Crysnanto, Stefan Neuenschwander, Andreas Hofer and Hubert Pausch

    Citation: BMC Genomics 2021 22:290

    Content type: Research

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  8. Chickpea, pigeonpea, and groundnut are the primary legume crops of semi-arid tropics (SAT) and their global productivity is severely affected by drought stress. The plant-specific NAC (NAM - no apical meristem...

    Authors: Sadhana Singh, Himabindu Kudapa, Vanika Garg and Rajeev K. Varshney

    Citation: BMC Genomics 2021 22:289

    Content type: Research article

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  9. Preweaned rumen development is vital for animal health and efficient fermentation. In this study, we integrated ruminal transcriptomic and metagenomic data to explore the dynamics of rumen functions, microbial...

    Authors: Xiangyu Pan, Zongjun Li, Bibo Li, Chen Zhao, Yu Wang, Yulin Chen and Yu Jiang

    Citation: BMC Genomics 2021 22:288

    Content type: Research article

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  10. Alanine:glyoxylate aminotransferase 2 (AGXT2; EC 2.6.1.44) is the only enzyme that degrades the R-form of 3-aminoisobutyrate, an intermediate metabolite of thymine. AGXT2, as well as diaminoarginine dimethylam...

    Authors: Yuta Yoshino, Hiroshi Kumon, Takaaki Mori, Taku Yoshida, Ayumi Tachibana, Hideaki Shimizu, Jun-ichi Iga and Shu-ichi Ueno

    Citation: BMC Genomics 2021 22:287

    Content type: Research

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  11. Analysis of lymphocyte cell lines revealed substantial differences in the expression of mRNA and microRNA (miRNA) among human populations. The extent of such population-associated differences in actual human t...

    Authors: Song Guo, Shuyun Huang, Xi Jiang, Haiyang Hu, Dingding Han, Carlos S. Moreno, Genevieve L. Fairbrother, David A. Hughes, Mark Stoneking and Philipp Khaitovich

    Citation: BMC Genomics 2021 22:286

    Content type: Research article

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  13. Night-break (NB) has been proven to repress flowering of short-day plants (SDPs). Long-noncoding RNAs (lncRNAs) play key roles in plant flowering. However, investigation of the relationship between lncRNAs and...

    Authors: Qi Wu, Yiming Luo, Xiaoyong Wu, Xue Bai, Xueling Ye, Changying Liu, Yan Wan, Dabing Xiang, Qiang Li, Liang Zou and Gang Zhao

    Citation: BMC Genomics 2021 22:284

    Content type: Research

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  14. Histone lysine methylation plays an important role in plant development and stress responses by activating or repressing gene expression. Histone lysine methylation is catalyzed by a class of SET-domain group ...

    Authors: Wenjie Li, Jinjiao Yan, Shicong Wang, Qianying Wang, Caixia Wang, Zhongxing Li, Dehui Zhang, Fengwang Ma, Qingmei Guan and Jidi Xu

    Citation: BMC Genomics 2021 22:283

    Content type: Research article

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  15. Cytidine monophospho-n-acetylneuraminic acid hydroxylase (CMAH) gene associated with blood groups in cats encodes CMAH enzyme that converts Neu5Ac to Neu5Gc. Although variations in CMAH gene of pedigree cats have...

    Authors: Hüseyin Can, Sedef Erkunt Alak, Ahmet Efe Köseoğlu, Umut Şahar, Berna Bostanbaş, Serdar Baydarlı, Mert Döşkaya and Cemal Ün

    Citation: BMC Genomics 2021 22:282

    Content type: Research article

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  16. Methionine (Met) supply during late-pregnancy enhances fetal development in utero and leads to greater rates of growth during the neonatal period. Due to its central role in coordinating nutrient and one-carbo...

    Authors: Valentino Palombo, Abdulrahman Alharthi, Fernanda Batistel, Claudia Parys, Jessie Guyader, Erminio Trevisi, Mariasilvia D’Andrea and Juan J. Loor

    Citation: BMC Genomics 2021 22:280

    Content type: Research article

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  17. Mammalian centromeres are satellite-rich chromatin domains that execute conserved roles in kinetochore assembly and chromosome segregation. Centromere satellites evolve rapidly between species, but little is k...

    Authors: Uma P. Arora, Caleigh Charlebois, Raman Akinyanju Lawal and Beth L. Dumont

    Citation: BMC Genomics 2021 22:279

    Content type: Research article

    Published on:

  18. Rice, which serves as a staple food for more than half of the world’s population, is grown worldwide. The hybridization of wild and cultivated rice has enabled the incorporation of resistance to varying enviro...

    Authors: Lei Tian, Enze Wang, Xiaolong Lin, Li Ji, Jingjing Chang, Hongping Chen, Jilin Wang, Dazhou Chen, Lam-Son Phan Tran and Chunjie Tian

    Citation: BMC Genomics 2021 22:278

    Content type: Research article

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  19. Heterosis has been exploited for decades in different crops due to resulting in dramatic increases in yield, but relatively little molecular evidence on this topic was reported in cotton.

    Authors: Yuanhao Ding, Rui Zhang, Longfu Zhu, Maojun Wang, Yizan Ma, Daojun Yuan, Nian Liu, Haiyan Hu, Ling Min and Xianlong Zhang

    Citation: BMC Genomics 2021 22:277

    Content type: Research article

    Published on:

  20. Stem rot caused by Sclerotium rolfsii is a very important soil-borne disease of peanut. S. rolfsii is a necrotrophic plant pathogenic fungus with an extensive host range and worldwide distribution. It can infect ...

    Authors: Liying Yan, Zhihui Wang, Wanduo Song, Pengmin Fan, Yanping Kang, Yong Lei, Liyun Wan, Dongxin Huai, Yuning Chen, Xin Wang, Hari Sudini and Boshou Liao

    Citation: BMC Genomics 2021 22:276

    Content type: Research article

    Published on:

  21. Sepsis is the major cause of death in Intensive Care Unit (ICU) globally. Molecular detection enables rapid diagnosis that allows early intervention to minimize the death rate. Recent studies showed that long ...

    Authors: Xubin Zheng, Kwong-Sak Leung, Man-Hon Wong and Lixin Cheng

    Citation: BMC Genomics 2021 22:275

    Content type: Research article

    Published on:

  22. Ectoparasites from the family Diplozoidae (Platyhelminthes, Monogenea) belong to obligate haematophagous helminths of cyprinid fish. Current knowledge of these worms is for the most part limited to their morph...

    Authors: Jiří Vorel, Krystyna Cwiklinski, Pavel Roudnický, Jana Ilgová, Lucie Jedličková, John P. Dalton, Libor Mikeš, Milan Gelnar and Martin Kašný

    Citation: BMC Genomics 2021 22:274

    Content type: Research

    Published on:

  24. Human cancer cell line profiling and drug sensitivity studies provide valuable information about the therapeutic potential of drugs and their possible mechanisms of action. The goal of those studies is to tran...

    Authors: Yuanyuan Li, David M. Umbach, Juno M. Krahn, Igor Shats, Xiaoling Li and Leping Li

    Citation: BMC Genomics 2021 22:272

    Content type: Research article

    Published on:

  25. Infestation by tea green leafhoppers (Empoasca (Matsumurasca) onukii) can cause a series of biochemical changes in tea leaves. As a typical cell-rupture feeder, E. onukii secretes proteases while using its stylet...

    Authors: Ensi Shao, Yujuan Song, Yaomin Wang, Yichen Liao, Yufei Luo, Sijun Liu, Xiong Guan and Zhipeng Huang

    Citation: BMC Genomics 2021 22:271

    Content type: Research article

    Published on:

  26. The number of myofiber is determined during the embryonic stage and does not increase during the postnatal period for birds, including goose. Thus, muscle production of adult goose is pre-determined during emb...

    Authors: Tieshan Xu, Zijie Xu, Lizhi Lu, Tao Zeng, Lihong Gu, Yongzhen Huang, Shunjin Zhang, Peng Yang, Yifan Wen, Dajie Lin, Manping Xing, Lili Huang, Guojun Liu, Zhe Chao and Weiping Sun

    Citation: BMC Genomics 2021 22:270

    Content type: Research article

    Published on:

  27. Uncovering the mechanisms underlying rapid genetic adaptation can provide insight into adaptive evolution and shed light on conservation, invasive species control, and natural resource management. However, it ...

    Authors: Xiaoshen Yin, Alexander S. Martinez, Maria S. Sepúlveda and Mark R. Christie

    Citation: BMC Genomics 2021 22:269

    Content type: Research article

    Published on:

  28. Fertilization in flowering plants depends on the early contact and acceptance of pollen grains by the receptive papilla cells of the stigma. Deciphering the specific transcriptomic response of both pollen and ...

    Authors: Chie Kodera, Jérémy Just, Martine Da Rocha, Antoine Larrieu, Lucie Riglet, Jonathan Legrand, Frédérique Rozier, Thierry Gaude and Isabelle Fobis-Loisy

    Citation: BMC Genomics 2021 22:268

    Content type: Research article

    Published on:

  29. The back plays a vital role in horse locomotion, where the spine functions as a spring during the stride cycle. A complex interaction between the spine and the muscles of the back contribute to locomotion soun...

    Authors: Maria K. Rosengren, Heiðrún Sigurðardóttir, Susanne Eriksson, Rakan Naboulsi, Ahmad Jouni, Miguel Novoa-Bravo, Elsa Albertsdóttir, Þorvaldur Kristjánsson, Marie Rhodin, Åsa Viklund, Brandon D. Velie, Juan J. Negro, Marina Solé and Gabriella Lindgren

    Citation: BMC Genomics 2021 22:267

    Content type: Research article

    Published on:

  30. The pathogen Listeria (L.) monocytogenes is known to survive heat, cold, high pressure, and other extreme conditions. Although the response of this pathogen to pH, osmotic, temperature, and oxidative stress has b...

    Authors: Bahareh Nikparvar, Margarita Andreevskaya, Ilhan C. Duru, Florentina I. Bucur, Leontina Grigore-Gurgu, Daniela Borda, Anca I. Nicolau, Christian U. Riedel, Petri Auvinen and Nadav Bar

    Citation: BMC Genomics 2021 22:266

    Content type: Research article

    Published on:

  31. Bacterial plant pathogens of the Pectobacterium genus are responsible for a wide spectrum of diseases in plants, including important crops such as potato, tomato, lettuce, and banana. Investigation of the genetic...

    Authors: Eef M. Jonkheer, Balázs Brankovics, Ilse M. Houwers, Jan M. van der Wolf, Peter J. M. Bonants, Robert A. M. Vreeburg, Robert Bollema, Jorn R. de Haan, Lidija Berke, Sandra Smit, Dick de Ridder and Theo A. J. van der Lee

    Citation: BMC Genomics 2021 22:265

    Content type: Research article

    Published on:

  32. Polyploid species often originate recurrently. While this is well known, there is little information on the extent to which distinct allotetraploid species formed from the same parent species differ in gene ex...

    Authors: Duo Chen, Peng-Cheng Yan and Yan-Ping Guo

    Citation: BMC Genomics 2021 22:264

    Content type: Research article

    Published on:

  34. Sweetpotato (Ipomoea batatas [L.] Lam.) is an important food crop. However, the genetic information of the nuclear genome of this species is difficult to determine accurately because of its large genome and compl...

    Authors: Shizhuo Xiao, Pan Xu, Yitong Deng, Xibin Dai, Lukuan Zhao, Bettina Heida, An Zhang, Zhilin Zhou and Qinghe Cao

    Citation: BMC Genomics 2021 22:262

    Content type: Research article

    Published on:

  35. Increases in ocean temperatures and in the frequency and severity of hypoxic events are expected with climate change, and may become a challenge for cultured Atlantic salmon and negatively affect their growth,...

    Authors: Anne Beemelmanns, Fábio S. Zanuzzo, Xi Xue, Rebeccah M. Sandrelli, Matthew L. Rise and A. Kurt Gamperl

    Citation: BMC Genomics 2021 22:261

    Content type: Research article

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  36. This correspondence responds to the critique by Butler et al. (BMC Genomics 22:241, 2021) of our recent paper on transposable element (TE) persistence. We address the three main objections raised by Butler et ...

    Authors: Stefan C. Kremer, Stefan Linquist, Brent Saylor, Tyler A. Elliott, T. Ryan Gregory and Karl Cottenie

    Citation: BMC Genomics 2021 22:260

    Content type: Correspondence

    Published on:

    The original article was published in BMC Genomics 2021 22:241

  37. Prior work demonstrated that female rats (but not their male littermates) exposed to methamphetamine become hypersensitive to myocardial ischemic injury. Importantly, this sex-dependent effect persists followi...

    Authors: Hasitha Chavva, Daniel A. Brazeau, James Denvir, Donald A. Primerano, Jun Fan, Sarah L. Seeley and Boyd R. Rorabaugh

    Citation: BMC Genomics 2021 22:259

    Content type: Research article

    Published on:

  38. Leaf color mutants are the ideal materials to explore the pathways of chlorophyll (Chl) metabolism, chloroplast development, and photosynthesis system. In this study, a spontaneous yellow-green leaf wucai (Brassi...

    Authors: Libing Nie, Yushan Zheng, Liting Zhang, Ying Wu, Shidong Zhu, Jinfeng Hou, Guohu Chen, Xiaoyan Tang, Chenggang Wang and Lingyun Yuan

    Citation: BMC Genomics 2021 22:258

    Content type: Research article

    Published on:

  39. Non-Drosophila insects provide diverse aging types and important complementary systems for studies of aging biology. However, little attention has been paid to the special roles of non-Drosophila insects in aging...

    Authors: Siyuan Guo, Pengcheng Yang, Bo Liang, Feng Zhou, Li Hou, Le Kang and Xianhui Wang

    Citation: BMC Genomics 2021 22:257

    Content type: Research article

    Published on:

  42. The differentiation of bone marrow mesenchymal stem cells is a complex and dynamic process. The gene expression pattern and mechanism of different periods of adipogenic and osteogenic differentiation remain un...

    Authors: Yu Liu, Markus Tingart, Sophie Lecouturier, Jianzhang Li and Jörg Eschweiler

    Citation: BMC Genomics 2021 22:254

    Content type: Research article

    Published on:

  43. Aedes aegypti mosquito, the principal global vector of arboviral diseases, lays eggs and undergoes larval and pupal development to become adult mosquitoes in fresh water (FW). It has recently been observed to dev...

    Authors: Ranjan Ramasamy, Vaikunthavasan Thiruchenthooran, Tibutius T. P. Jayadas, Thampoe Eswaramohan, Sharanga Santhirasegaram, Kokila Sivabalakrishnan, Arunasalam Naguleswaran, Marilyne Uzest, Bastien Cayrol, Sebastien N. Voisin, Philippe Bulet and Sinnathamby N. Surendran

    Citation: BMC Genomics 2021 22:253

    Content type: Research article

    Published on:

  44. Plant transitions to land require robust cell walls for regulatory adaptations and to resist changing environments. Cell walls provide essential plasticity for plant cell division and defense, which are often ...

    Authors: Wenjun Sun, Haomiao Yu, Moyang Liu, Zhaotang Ma and Hui Chen

    Citation: BMC Genomics 2021 22:252

    Content type: Research article

    Published on:

  46. Trichophyton mentagrophyte (TM), a zoonotic pathogen, has been endangering public health due to emerging drug resistance. Although increased attention is paid to this issue, there is very limited research avai...

    Authors: Chenwen Xiao, Jiaoyu Wang, Zhenfeng Liao, Yee Huang, Quanan Ji, Yan Liu, Fei Su, Lijun Xu, Qiang Wei, Yao Pan, Ke Li and Guolian Bao

    Citation: BMC Genomics 2021 22:250

    Content type: Research article

    Published on:

  47. The blood feeding poultry red mite (PRM), Dermanyssus gallinae, causes substantial economic damage to the egg laying industry worldwide, and is a serious welfare concern for laying hens and poultry house workers....

    Authors: Kathryn Bartley, Wan Chen, Richard I. Lloyd Mills, Francesca Nunn, Daniel R. G. Price, Stephane Rombauts, Yves Van de Peer, Lise Roy, Alasdair J. Nisbet and Stewart T. G. Burgess

    Citation: BMC Genomics 2021 22:248

    Content type: Research article

    Published on:

  48. Infectious bronchitis virus (IBV) is one of the most relevant viruses affecting the poultry industry, and several studies have investigated the factors involved in its biological cycle and evolution. However, ...

    Authors: Giovanni Franzo, Claudia Maria Tucciarone, Matteo Legnardi and Mattia Cecchinato

    Citation: BMC Genomics 2021 22:244

    Content type: Research article

    Published on:

  49. Plant pathogenic isolates of Rhizoctonia solani anastomosis group 1-intraspecific group IA (AG1-IA) infect a wide range of crops causing diseases such as rice sheath blight (ShB). ShB has become a serious disease...

    Authors: Da-Young Lee, Jongbum Jeon, Ki-Tae Kim, Kyeongchae Cheong, Hyeunjeong Song, Gobong Choi, Jaeho Ko, Stephen O. Opiyo, James C. Correll, Shimin Zuo, Sheshu Madhav, Guo-Liang Wang and Yong-Hwan Lee

    Citation: BMC Genomics 2021 22:242

    Content type: Research article

    Published on:

  50. Transposable elements are significant components of most organism’s genomes, yet the reasons why their abundances vary significantly among species is poorly understood. A recent study has suggested that even i...

    Authors: Christopher L. Butler, Ellen A. Bell and Martin I. Taylor

    Citation: BMC Genomics 2021 22:241

    Content type: Correspondence

    Published on:

    The original article was published in BMC Genomics 2020 21:367

    The Correspondence to this article has been published in BMC Genomics 2021 22:260

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