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Table 2 Amino acid homology of neurotoxin A subtypes.

From: Independent evolution of neurotoxin and flagellar genetic loci in proteolytic Clostridium botulinum

Strain

ATCC 3502

Hall 183

CDC 297

Kyoto F

NCTC 2012

CDC 657

H0 4402 065

ATCC 3502

100.0 (0)

      

Hall 183

99.8 (2)

100.0 (0)

     

CDC 297

99.6 (5)

99.6 (5)

100.0 (0)

    

Kyoto F

90.0 (130)

89.8 (132)

89.7 (134)

100.0 (0)

   

NCTC 2012

84.4 (202)

84.3 (204)

84.2 (205)

93.0 (91)

100.0 (0)

  

CDC 657

89.1 (141)

89.0 (143)

89.0 (142)

88.1 (154)

84.1 (206)

100.0 (0)

 

H0 4402 065

97.1 (37)

97.1 (38)

96.9 (40)

90.3 (125)

84.9 (196)

87.3 (165)

100.0 (0)

  1. Pair-wise comparison of 1296 amino acid residue type A neurotoxins. ATCC 3502, Hall 183, CDC 297, type A1; Kyoto F, type A2; NCTC 2012, type A3; CDC 657, type A4; H0 4402 065, type A5. Bold figures: percent homology; figures in brackets: number of different residues. Only unique data are shown; A1 neurotoxins identical to that of strain ATCC 3502 include those of strains NCTC 3805 (62A), NCTC 7272 (ATCC 19397), and ATCC 25763. The A1 neurotoxin of Hall 183 is identical to that of the A1 (B) strain NCTC 2916. The Kyoto F A2 neurotoxin is identical to that of the FRI-Honey strain (all sequence data from GenBank). All type A5 neurotoxins described in this study are identical.