An improved method for genome wide DNA methylation profiling correlated to transcription and genomic instability in two breast cancer cell lines

Table 2 Comparison of the methylation states based on significantly different individual genomic sites

The individual genomic sites with significantly different number of tags between two cell lines were collected and classified to the corresponding genomic categories. Then a T-test statistical analysis was performed to test the difference of the methylation states of promoters (including the promoters with CGIs and without CGIs), introns, exons and CGIs (no promoters) between both cell lines. 5. The number of individually significantly different genomic sites involved for a give category is shown. The meanings of the P-value and mean in Table 2 are the same as in Table 1.

ISSN: 1471-2164